|
Pediatric HIV Infection
by Mark W. Kline, M.D.
1. Introduction
Important features distinguish human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS) in infants and children from the disease observed in adults. Vertical transmission of HIV and the effects of the virus on an immature and naive immune system undoubtedly influence disease expression in ways that as yet are poorly defined. Difficulties in confirming the diagnosis of HIV infection in early infancy, and rapid disease progression in infants with vertically acquired infection, limit opportunities for early therapeutic intervention. In addition, HIV has important adverse effects on the developing central nervous system and normal linear growth and weight gain.
2. Clinical Manifestations
3. Diagnosis
|
